In Vivo Nucleic Acid Delivery Vehicle

Proprietary formulation composed of neutral lipid, non-ionic detergent, oil and small molecules which enable highly efficient delivery of RNAi agents into animals. This novel product has been shown to be more robust and efficient at penetrating tissues and organs than other delivery agents. When manufacturing this reagent, all components of the formulation are dissolved and mixed in an organic solvent to obtain a homogeneous mixture. The intent is to obtain a clear soluble suspension of the components. Once the components are mixed, the organic solvent is completely removed to yield a semi-dry solution which is supplied to the customer in 4 glass vials in the kit. Each vial has enough material for 5 injections (20 injections total). Formulation proven to work in mouse model systems with siRNAs. Long track record and publication history for its utility.