COVID-19

New-onset IgG autoantibodies in hospitalized patients with COVID-19

COVID-19 is associated with a wide range of clinical manifestations, including autoimmune features and autoantibody production. Here this group develop three protein arrays to measure IgG autoantibodies associated with connective tissue diseases, anti-cytokine antibodies, and anti-viral antibody responses in serum from 147 hospitalized COVID-19 patients. Autoantibodies are identified in approximately 50% of patients but in […]

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SARS-CoV-2 Variant Classifications and Definitions

SARS-CoV-2 Variant Classifications and Definitions Key Points: Genetic variants of SARS-CoV-2 have been emerging and circulating around the world throughout the COVID-19 pandemic. Viral mutations and variants in the United States are routinely monitored through sequence-based surveillance, laboratory studies, and epidemiological investigations. A US government interagency group developed a Variant Classification scheme that defines three

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SARS-CoV-2 Mutations – Cause for Concern?

The accumulation of genetic mutations is a normal part of viral evolution. Mutations change the sequence of the viral genome, creating different ‘variants.’ While some mutations might be silent, with no visible clinical effect, others might have implications for disease transmission, severity, reinfection potential, and immunity. SARS-CoV-2 variants A recently described clinically significant mutation has

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Effectiveness of Medical and Cloth Masks for COVID-19 Protection

ToolsWebinar_Flyer_Effectiveness of Masks for COVID-19 Protection   Despite widespread adoption of face mask use for personal protection and to help stop the spread of COVID-19, there is little or no public information available on the performance and efficacy of different types of masks or modifications on existing face coverings. Important questions, such as which type

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