High quality products to support Pathologists and Biological and Environmental Scientists
GeneAb™ HER2/neu
$90.00 – $450.00The HER2/neu (c-erbB-2) proto-oncogene is a transmembrane receptor tyrosine kinase that is clinically indicated in a number of carcinomas. Overexpression of the c-erbB-2 protein has been associated with ductal breast cancer, as well as pulmonary and gastric adenocarcinomas. A correlation between HER2 and p53 has also been documented, as overexpression of both proteins has been associated with early invasion and metastasis in bladder cancer.
GeneAb™ Cytokeratin 7
$95.00 – $420.00Cytokeratin 7 (CK7) is a type II keratin which is present in transitional, ductal, glandular, and biliary duct epithelial cells. Cytokeratin 7 is a useful marker for distinguishing between carcinomas of the lung, breast, endometrium, and urothelia (positive stain) from carcinomas of the colon and prostate (negative stain). Cytokeratin 7 is present in nearly all primary lung adenocarcinomas, and is a useful marker in the differential diagnosis of ovarian neoplasms. Anti-Cytokeratin 7 does not stain intermediate filament.
GeneAb™ CTLA-4
$120.00 – $920.00Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA-4) is a receptor on T helper cells that functions as an immune checkpoint and downregulator of immune responses. Mutations in CTLA-4 are associated with insulin-dependent diabetes mellitus, Hashimoto’s thyroiditis, Graves’ disease, systemic lupus erythematosus (SLE), celiac disease, primary biliary cirrhosis, thyroid-associated orbitopathy, multiple sclerosis, and other autoimmune diseases. The spliced variant of CTLA-4 in SLE is present in the patient’s serum. Haploinsufficiency of CTLA-4 causes the immune system disorder known as CTLA-4 deficiency or CHAI disease (CTLA-4 haploinsufficiency with autoimmune infiltration).
SNPsig® EscapePLEX™ SARS-CoV-2
$1,505.00Product Features
- Rapid detection of specific detection profiles
- High priming efficiency
- Sensitive to < 100 copies of target
- Positive copy number standard curve for quantification
- Accurate controls to confirm findings
- 96 reactions
SNPsig® COVID-19 (20I/501Y.V1+E484K) Identification Kit
$1,500.00- For the detection of the SARS-CoV-2 variants with the 20I/501Y.V1, VOC-21FEB-02 and variants carrying the E484K mutation
- Rapid detection of specific detection profiles
- High priming efficiency
- Sensitive to < 100 copies of target
- Positive copy number standard curve for quantification
- Accurate controls to confirm findings
- 96 reactions, includes master mix
SNPsig® SARS-CoV-2 (VUI-21APR) Identification Kit
$1,500.00- For the detection of the SARS-CoV-2 variants with the VUI-21APR-01 and VUI-21APR-03 (India)
- Rapid detection of specific detection profiles
- High priming efficiency
- Sensitive to < 100 copies of target
- Positive copy number standard curve for quantification
- Accurate controls to confirm findings
- 96 reactions, includes master mix
SNPsig® SARS-CoV-2 (20B/484K) Identification Kit
$1,500.00- Detection of the SARS-CoV-2 variants with the 20B/S.484K mutation, also known as P2
- Rapid detection of specific detection profiles
- High priming efficiency
- Sensitive to < 100 copies of target
- Positive copy number standard curve for quantification
- Accurate controls to confirm findings
- 96 reactions, includes master mix
SNPsig® SARS-CoV-2 (L452R) Identification Kit
$1,500.00- For the detection of the SARS-CoV-2 variants with the L452R mutation
- Rapid detection of specific detection profiles
- High priming efficiency
- Sensitive to < 100 copies of target
- Positive copy number standard curve for quantification
- Accurate controls to confirm findings
- 96 reactions, includes master mix