GeneAb™ TFE3
$55.00 – $300.00
In Stock & Ready to Ship
Transcription Factor E3 (TFE3) is a transcription factor that binds to the MUE3-type E-box sequences involved in TGF-β signalling. Anti-TFE3 staining is the most sensitive and specific indicator of Xp11 translocation renal cell carcinomas. Since alveolar soft part sarcoma (ASPS) is characterized by a specific chromosomal rearrangement resulting in a chimeric transcription factor (ASPSCR1-TFE3), this TFE3 IVD antibody is also a useful diagnostic tool for recognizing ASPS.
Specifications
| Clone | IHC672 |
| Source | Mouse Monoclonal |
| Positive Control | Testes, Melanoma, Xp11.2 Translocation Renal Cell Carcinoma |
| Dilution Range | 1:100 – 1:200 |
IFU & SDS
References
- Argani P, et al. Am J Clin Pathol. 2006; 126:332-4.
- Argani P, et al. Am J Surg Pathol. 2003; 27:750-61.
- Lazar AJ, et al. Histopathology. 2009; 55:750-5.
