GeneAb™ SOX10

$100.00$415.00

In Stock & Ready to Ship

SRY (Sex Determining Region Y)-Box 10 (SOX-10), also known as transcription factor SOX-10, is a nuclear transcription factor that acts in regulation of embryonic development and in the specification and differentiation of cells of melanocytic lineage. SOX-10 is diffusely expressed in neurofibromas and schwannomas, and mutations in the SOX-10 gene are linked to Waardenburg-Shah and Waardenburg-Hirschsprung disease. Anti-SOX-10 has been shown to be sensitive for conventional, spindled, and desmoplastic melanoma, and has been used to detect metastatic melanoma and nodal capsular nevus in sentinel lymph nodes.

Share:
Clear
Compare

Specifications

 

Clone IHC010
Source Mouse Monoclonal
Positive Control Melanoma, Skin Melanocytes
Dilution Range 1:200