GeneAb™ p21


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p21, also known as p21Cip1 , p21Waf1, cyclin-dependent kinase inhibitor 1, or CDK-interacting protein 1, functions to regulate cell cycle progression at G1 by inhibiting the activity of Cyclin-CDK2 or -CDK4 complexes. This cyclin-dependent kinase inhibitor is expressed in all adult human tissues, and decreased expression of p21 is linked to poor prognosis in a number of carcinomas including gastric carcinoma, non-small cell lung carcinoma and thyroid carcinoma. p21 is also associated with favorable prognosis in several tumors.

SKU: IHC021 Categories: ,


Clone IHC021
Source Mouse Monoclonal
Positive Control Colon Carcinoma
Dilution Range 1:100 – 1:200
  • References

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