GeneAb™ CD45R

$65.00$210.00

Description

CD45R, also known as MB1, is an isoform of CD45 that is a member of the protein tyrosine phosphatase (PTPase) family. CD45R is expressed specifically on the surface of hematopoietic cells, and has demonstrated function as a regulator of the antigen and cytokine receptor signalling of B and T cells. Given that the antigen is located in the membrane of all B cells, with the exception of plasma cells and some mature T cells, Anti-CD45R exhibits specific reactivity with most B lymphocytes. The use of Anti-CD45R is primarily useful in distinguishing B cell lymphomas from T cell lymphomas, with specific reactivity to follicle center cells, mantle cells, some medullary thymocytes, and 80% of B cell lymphomas.

Clear
SKU: IHC100-2 Categories: ,

Description

Specifications

CloneIHC536
SourceMouse Monoclonal
Positive ControlLymph Node, Tonsil
Dilution Range1:100 – 1:400

IFU & SDS

References

  1. Myskow M, et al. Am J Clin Pathol. 1988; 90:564-74.
  2. Shin S, et al. Hum Pathol. 1992; 23:686-94.

Additional information

Select Volume

0.1ml C, 1ml C, 7ml P, 25ml P